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Where does thermal noise come from? The physical origin of thermal noise (or Johnson noise, or Nyquist noise) is explained. I use the example of installing a cryogenic RF receiver front-end to illustrate the cascaded noise figure of a radio receiver front end. A cascaded noise figure example is presented using the Friis equation. Here is the link for my entire course on "Semiconductor Devices for VLSI" 🤍 This is Lecture 66 of 77. Any textbook references are to the free e-book "Modern Semiconductor Devices for Integrated Circuits" by Chenming Calvin Hu. #NoiseFigure #ThermalNoise #NoiseFactor #CryogenicReceiverFrontEnd #SignalToNoiseRatio
Director Quantum Applications Dr Russell E Lake's talk was featured virtually as one of the exhibitor workshops at the APS March Meeting 2022 on March 15. This talk presents recent developments in cryogenic measurement infrastructure in the Bluefors system. Highlights include high density interconnects, filtering, cryogenic diagnostic tools, and ultralow noise microwave readout. These components are discussed in terms of system integration, quantum measurement applications, and forward-compatibility with large scale cooling platforms. Follow our website and social media channels for the latest updates: Website: 🤍 LinkedIn: 🤍 Twitter: 🤍 Facebook: 🤍 Instagram: 🤍 YouTube channel: 🤍
Abstract: Quantum computers operate by processing information stored in quantum bits (qubits), which must typically operate at cryogenic temperature. A practical quantum computer will comprise thousands of qubits, thus requiring an electronic interface also operating at cryogenic temperature to ensure integration and scalability of the whole system. Focusing on the use of standard CMOS technology, we will explore the challenges in building such interface, comprising modeling of the quantum/classical interface, devices modeling for cryogenic CMOS and the design of high-performance cryogenic CMOS circuits. By demonstrating the cryogenic operation of complex CMOS analog and digital systems, we will show that cryogenic CMOS is a viable technology to enable large-scale quantum computing. Bio: Fabio Sebastiano holds degrees in Electrical Engineering from University of Pisa, Italy (BSc, 2003; MSc, 2005) from Sant’Anna school of Advanced Studies, Pisa, Italy (MSc, 2006) and from Delft University of Technology, The Netherlands (PhD, 2011). From 2006 to 2013, he was with NXP Semiconductors Research in Eindhoven, The Netherlands. In 2013, he joined Delft University of Technology, where he is currently an Assistant Professor. He has authored or co-authored one book, ten patents, and over 60 technical publications. His main research interests are cryogenic electronics for quantum applications, sensor read-outs and frequency references. Dr. Sebastiano was the co-recipient of the best student paper award at ISCAS in 2008, the best paper award at IWASI in 2017 and the best IP award at DATE in 2018. He is a senior member of IEEE, a TPC member for RFIC and a Distinguished Lecturer of the IEEE Solid-State Circuit Society.
Shirin Montazeri PhD, Research Scientist, Google
Sjors Scheres' group is interested in developing methods that allow visualisation of macromolecular machines in their multitude of natural states in order to understand how they work, as well as using these methods to determine the structures of unfolded amyloid proteins that are extracted from the brains of individuals with neurodegenerative diseases, like Alzheimer's and Pick's disease. Sjors is the main developer of RELION, a popular software package for cryo-EM structure determination. Read more about Sjors' work here: 🤍 Read more about RELION here: 🤍 Download the lecture presentation here: 🤍 You can find more videos from the 2017 LMB Cryo-EM course here: 🤍 Other playlists you might be interested in: Electron Cryo-Microscopy Course 2014 - 🤍 Electron Cryo-Microscopy - 🤍 RELION - 🤍 Research Highlights from our Structural Studies Division - 🤍 About the MRC Laboratory of Molecular Biology (LMB): The LMB is one of the world's leading research institutes. Discoveries and inventions developed at the LMB, for example DNA sequencing and methods to determine the structure of proteins, have revolutionised all areas of biology. Its scientists work to advance understanding of biological processes at the molecular level. This information will help us to understand the workings of complex systems, such as the immune system and the brain, and solve key problems in human health. More links: Official Site: 🤍 Facebook: 🤍 Twitter: 🤍 Instagram: 🤍 LinkedIn: 🤍 Click here to subscribe to MRC Laboratory of Molecular Biology on YouTube: 🤍
Noise is a fundamental property of electronic circuits. This video investigates how the thermal motion of electrons in a resistor produces noise. Simulations of random electron motion in a resistor provide powerful visuals. Additional reference material is available at 🤍
In part of the electronics tutorial video I start working on the Low noise signal amplifier by looking at some potential op-ams to use based on their noise performance and then simulating the circuit using LTspice to see if it actually works. Final schematic simulation: 🤍 Also in this miniseries: Ep1: 🤍 Ep2: 🤍 Ep3: 🤍 Datasheets analysed: 🤍 🤍 🤍 🤍 🤍 If you liked this video be sure to check out my other videos and you can also subscribe to be up to date with all the new ones! If you want to support the creation of more and better videos you can at: 🤍 Music: The Builder by Kevin MacLeod 🤍 Creative Commons — Attribution 3.0 Unported — CC BY 3.0 Free Download / Stream: 🤍 Music promoted by Audio Library 🤍
Cryogenic LNA manufactured by Callisto France. - In different bands (X, K, Ka), - Suitable for remote location, - No maintenance for 10 years, - Low Power Consumption, - 1 or 2 RF channels, Please visit our website at 🤍 for more details on this product.
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Control of transmon qubits using a cryogenic CMOS integrated circuit talk is presented by Research Scientist Joe Bardin for the APS March Meeting 2020. Superconducting quantum processors are controlled and measured in the analog domain and the design of the associated classical-to-quantum interface is critical in optimizing the overall performance of the quantum computer. Control of the processor is achieved using a combination of carefully shaped microwave pulses and high-precision time varying flux biases. Measurement of quantum states is typically achieved using dispersive readout, which requires a low-power pulsed microwave drive and a near quantum-limited readout chain. For control of a single qubit, a typical system employs two high-speed high-resolution (e.g., 1 Gsps/14 bit) digital-to-analog converters (DACs) and a single-sideband modulator to generate microwave control pulses. A third DAC with similar specifications is used for flux-bias control. A typical readout channel may service on the order of five qubits and contains yet another pair of DACs, with a single-sideband modulator employed to generate a stimulus signal. For measurement, the readout chain also employs a series of cryogenic amplifiers followed by further amplification, IQ demodulation, and high-speed digitization at room temperature. For today’s prototype systems with on the order of 50-100 qubits, keeping most of the electronics at room temperature makes sense. However, achieving fault tolerance—a long term goal of the community—will require implementing systems with on the order of 10^6 qubits and today’s brute force control and readout approach will not scale to these levels. Instead, a more integrated approach will be required. In this talk, we will present a review of recent work towards implementing a scalable cryogenic quantum control and readout system using silicon integrated circuit technology. After motivating the work, we will describe the design and characterization of a prototype cryogenic XY controller for transmon qubits. Detailed measurement results will be presented. The talk will conclude with a discussion of future work. Watch every episode of QuantumCasts here → 🤍 Subscribe to the TensorFlow channel → 🤍
Analog Circuit Design (New 2019) Professor Ali Hajimiri California Institute of Technology (Caltech) 🤍 © Copyright, Ali Hajimiri
Ice SLOWS the healing process. Learn why today. Get my book on fixing injury here: 🤍 Get my book 'The Squat Bible' here: 🤍 Get my 13-Week Squat Program? 🤍 Get olympic weightlifting programming (part 1): 🤍 Get olympic weightlifting programming (part 2): 🤍 Show Sponsors - TYR: 🤍 - Bandbell: Check out their amazing bars here: 🤍 Subscribe to the channel: 🤍 Check out the Eleiko products I use here: 🤍 Recommended products: 🤍 FitMap: 🤍 Support SquatU & join monthly live Q&A: 🤍 Connect with SquatUniversity: Visit the website: 🤍 Like the Facebook page: 🤍 Follow on Twitter: 🤍 Follow on TikTok: 🤍SquatUniversity Follow on Instagram: 🤍 Listen to the Podcast on: apple iTunes, Overcast, Pocket Casts, Google Play and the Anchor App
This video will help you do the LNA simulations in a right way. Explains how the loading from mixer has to be included in the simulations.
Miley Cyrus disrespects Joe Rogan on the JRE Podcast saying he "always does the same stuff". SideShorts: 🤍 #shorts
Dr. Kevin Obrien presented on approaching the quantum limits for amplification and isolation with nonlinear metamaterials on February 18, 2021. Instagram: 🤍 Twitter: 🤍 LinkedIn: 🤍 Facebook: 🤍 More Berkeley Lab news: 🤍 Subscribe: 🤍
Sjors Scheres' group is interested in developing methods that allow visualisation of macromolecular machines in their multitude of natural states in order to understand how they work, as well as using these methods to determine the structures of unfolded amyloid proteins that are extracted from the brains of individuals with neurodegenerative diseases, like Alzheimer's and Pick's disease. Sjors is the main developer of RELION, a popular software package for cryo-EM structure determination. Read more about Sjors' work here: 🤍 Read more about RELION here: 🤍 You can find more videos from the 2014 LMB Cryo-EM course here: 🤍 Other playlists you might be interested in: Electron Cryo-Microscopy Course 2017 - 🤍 Electron Cryo-Microscopy - 🤍 RELION - 🤍 Research Highlights from our Structural Studies Division - 🤍 About the MRC Laboratory of Molecular Biology (LMB): The LMB is one of the world's leading research institutes. Discoveries and inventions developed at the LMB, for example DNA sequencing and methods to determine the structure of proteins, have revolutionised all areas of biology. Its scientists work to advance understanding of biological processes at the molecular level. This information will help us to understand the workings of complex systems, such as the immune system and the brain, and solve key problems in human health. More links: Official Site: 🤍 Facebook: 🤍 Twitter: 🤍 Instagram: 🤍 LinkedIn: 🤍 Click here to subscribe to MRC Laboratory of Molecular Biology on YouTube: 🤍
Richard Henderson's group aims to determine the atomic structure of interesting or important membrane proteins and membrane protein complexes, and is interested in the improvement of methods for high resolution electron cryo-microscopy. Read more about Richard's work here: 🤍 You can find more videos from the 2014 LMB Cryo-EM course here: 🤍 Other playlists you might be interested in: Electron Cryo-Microscopy Course 2017 - 🤍 Electron Cryo-Microscopy - 🤍 RELION - 🤍 Research Highlights from our Structural Studies Division - 🤍 About the MRC Laboratory of Molecular Biology (LMB): The LMB is one of the world's leading research institutes. Discoveries and inventions developed at the LMB, for example DNA sequencing and methods to determine the structure of proteins, have revolutionised all areas of biology. Its scientists work to advance understanding of biological processes at the molecular level. This information will help us to understand the workings of complex systems, such as the immune system and the brain, and solve key problems in human health. More links: Official Site: 🤍 Facebook: 🤍 Twitter: 🤍 Instagram: 🤍 LinkedIn: 🤍 Click here to subscribe to MRC Laboratory of Molecular Biology on YouTube: 🤍
In this QuTech360 seminar, Fabio Sebastiano, Group leader and Research lead in the Quantum Computing Division at QuTech, discusses Cryo-CMOS electrical interfaces for quantum processors. For bio and abstract, please see the description below. Title: Cryo-CMOS electrical interfaces for quantum processors Speaker: Fabio Sebastiano Abstract: As the qubit count in today’s quantum processors keeps steadily rising, it is increasingly challenging to control and read out such a large number of cryogenic qubits with off-the-shelf room-temperature electronics. Such an approach will soon hit a brick wall due to the limited reliability and the sheer size of the cables interconnecting the quantum processor to its electronic interface for a large-scale quantum computer with thousands or even millions of qubits. As a scaling-friendly alternative, we propose an electronic controller fabricated using commercial CMOS technology but operating at cryogenic temperatures close to the qubits, thus leveraging the very large scale of integration of the semiconductor industry. In this talk, the main challenges in building the cryo-CMOS electronics for a large-scale quantum computer will be first outlined. Then, several analog/mixed-signal/digital circuits and complex SoCs operating at cryogenic temperature and in combination with qubits will be demonstrated, thus showing that CMOS technology is a viable and necessary element to enable large-scale quantum computing. Bio: Fabio Sebastiano received the B.Sc. and M.Sc. degrees in electrical engineering from University of Pisa, Italy, in 2003 and 2005, respectively, the M.Sc. degree (cum laude) from Sant’Anna School of Advanced Studies, Pisa, Italy, in 2006 and the Ph.D. degree from Delft University of Technology, The Netherlands, in 2011. From 2006 to 2013, he was with NXP Semiconductors Research in Eindhoven, The Netherlands, where he researched fully integrated CMOS frequency references, nanometer temperature sensors, and area-efficient interfaces for magnetic sensors. In 2013, he joined Delft University of Technology, where he is currently an Associate Professor and the Research Lead of the Quantum Computing Division of QuTech. His main research interests are cryogenic electronics, quantum computing, sensor read-outs, and fully integrated frequency references. Dr. Sebastiano is on the technical program committee of the ISSCC, the RFIC Symposium, and the IMS, and he is currently serving as an Associate Editor of the IEEE Transactions on VLSI. He was co-recipient of the 2008 ISCAS Best Student Paper Award, the 2017 DATE best IP award, and the ISSCC 2020 Jan van Vessem Award for Outstanding European Paper. He has served as Distinguished Lecturer of the IEEE Solid-State Circuit Society. ABOUT QuTech360 seminars: QuTech360 is a series of seminars where people of all QuTech divisions have the opportunity to build a deep understanding of the topics researched at QuTech. In each seminar, a quantum expert will guide us through one of the main topics studied in their group. Visit us at 🤍 and follow us on social media! Do you want to learn more about quantum? - take our free online courses at 🤍 - visit our new quantum learning platform at 🤍
Imagine a shiny modern airliner crisscrossing the globe powered exclusively by clean electricity and fresh air. That’s the grand vision of a new generation of jet thrusters making big noise in engineering labs around the world. But is this technology the solution to runaway climate change and fossil fuel dependency – or just a load of hot air? Join us today as we take a metaphorical test flight with the electric plasma jet engine. SUGGEST A TOPIC 🤍 Imagery supplied via Getty Images What Are Electric Plasma Jet Engines?
Learn more about General Relativity at One Hundred: The Sixth Biennial Francis Bacon Conference held at Caltech and The Huntington Library, Art Collections and Botanical Gardens from March 10 -12, 2016: 🤍 Footage provided by Les Guthman. All rights reserved by XPLR Production and the Advanced LIGO Documentary Project. Produced in association with Caltech Academic Media Technologies. ©2016 California Institute of Technology
Interfacing Superconducting Quantum Circuits with an RF Photonic Link Your formal invite to weekly Qiskit videos ► 🤍 Speaker: John Teufel Host: Zlatko Minev, Ph.D. From the early days of superconducting qubits, one of their most attractive attributes was the inherent scalability of nanofabricated quantum circuits. If these engineered quantum devices could demonstrate sufficient coherence and quantum control, scaling to thousands or even millions of qubits should be a straightforward engineering task. Today, superconducting qubits have progressed so rapidly that they are beginning to outgrow the cryostats in which they are housed. I will discuss how cryogenic RF photonic links offer a scalable alternative to traditional coaxial wiring for the control and readout a transmon qubits [1]. I will also discuss several ongoing experimental efforts at NIST Boulder to extend the quantum technology from microwave frequencies to other unused parts of the electromagnetic spectrum. This includes lower frequency (MHz) mechanical devices and higher frequency (millimeter wave) circuits for applications including the processing, storage and networking of quantum information. [1] F. Lecocq, et al, Nature 591, 575-579 (2021) The Qiskit Seminar Series is a deep dive into various academic and research topics within the quantum community. It will feature community members and leaders every Friday, 12 PM EDT.
UPDATE: Questions about why we were doing what we were doing? Please see the FAQ under "MRI magnet quench: the movie." That video is also entertaining, btw. Fun, games and safety implications with a 4 tesla (T) MRI magnet that was about to be decommissioned. Note how magnetic objects let loose tend to oscillate along the magnet bore. That's because the peak magnetic field gradients are at either end (near the magnet face), causing peak acceleration as the object enters, followed by progressively damped changes of direction. See practiCalfMRI.blogspot.com for more information.
LNA cooling experiment to see how the Noise Figure decrease as more cool is the low noise amplifier.
A review of the electrical and thermal behavior of MOSFET devices operated from 300 K down to 3.1 K is introduced. The Physics behind of the electrical performance correlated to the self heating and cross coupled electro-thermal performance is also introduced. Experimental and modeling results of the different thermal paths encountered by the heat diffusing away from the hot spot is also commented. Finally I introduce experimental data from a 65nm bulk device and a 14nm FinFet device. The experimental data serves as a reference to determine the possible application of advanced CMOS technologies for quantum computing.
Noise Module (2/3): Noise Factor Noise Figure Equivalent Noise Temperature Noise factor of a Cascade of Amplifiers Noise Temperature of a Cascade of Amplifiers (Friis Equation)
This talk was part of the of the online workshop on "DARK MATTER: From Theory to Detection" held July 7 - 16, 2021. An ISAPP school on theories and laboratory tests of dark matter. This astroparticle physics graduate school will cover important and timely topics that are connected to the Dark Matter problem, taught by internationally renowned experts. A primary focus of the school will be on the direct detection of dark matter (DM) in rare-event searches. The theoretical background, observational motivation, and experimental avenues to observe dark matter signatures in the laboratory will be covered. Lectures will be complemented with hands-on sessions and student projects. The duration of the school is 10 days.
Alan Brown's group's long-term goal is to understand transport mechanisms in the cell, with a particular interest in the interplay between microtubules, motor proteins, adaptor complexes and their cargoes. To do this they use a combination of structural, biophysical and biochemical techniques with an emphasis on high-resolution electron microscopy. They are also interested in developing new methods to accelerate and improve cryo-EM structure determination, in particular by improving the interpretation of cryo-EM density maps with all-atom models. Read more about Alan's work here: 🤍 Download the lecture presentation here; 🤍 You can find more videos from the 2017 LMB Cryo-EM course here: 🤍 Other playlists you might be interested in: Electron Cryo-Microscopy Course 2014 - 🤍 Electron Cryo-Microscopy - 🤍 RELION - 🤍 Research Highlights from our Structural Studies Division - 🤍 About the MRC Laboratory of Molecular Biology (LMB): The LMB is one of the world's leading research institutes. Discoveries and inventions developed at the LMB, for example DNA sequencing and methods to determine the structure of proteins, have revolutionised all areas of biology. Its scientists work to advance understanding of biological processes at the molecular level. This information will help us to understand the workings of complex systems, such as the immune system and the brain, and solve key problems in human health. More links: Official Site: 🤍 Facebook: 🤍 Twitter: 🤍 Instagram: 🤍 LinkedIn: 🤍 Click here to subscribe to MRC Laboratory of Molecular Biology on YouTube: 🤍
Video courtesy of S2C2 (Stanford-SLAC Cryo-EM Center) Cryo-EM Image Processing Workshop - June 10-12, 2020. Workshop agenda: 🤍 00:39 Introduction 14:04 Documentation & user support 22:17 User interface overview 40:35 Cryo-EM data processing (background) 50:33 Basic T20S tutorial: Introduction 1:01:06 Import movies 1:30:55 Motion correction 2:00:14 CTF estimation 2:17:52 Exposure curation 2:39:41 Particle picking 3:33:10 2D classification 3:48:32 Ab-initio reconstruction 4:19:08 Refinement Browse additional cryoSPARC tutorial videos at: 🤍
Talk by 2006 Nobel laureate in Chemistry Roger Kornberg, Stanford University, at the Nobel Workshop “Molecules in Nano and Energy Research” at Chalmers University of Technology in Gothenburg, Sweden on May 5, 2015. The workshop was part of a historical event called “An Amazing Week at Chalmers” with 40 speakers, including 12 Nobel laureates.
Paul Marsh, M0EYT gives an introduction into deep space mega-DX, the equipment needed and the techniques used to identify extremely weak signals coming from man-made space probes in various parts of our solar system. X-Band (8.4GHz) is the primary band of discussion but Paul also talks briefly about S and Ka reception equipment and antennas. You can receive signals from spacecraft in excess of 1 billion Km with a modest size dish in your garden. If you have an interest in EME or microwave weak signal reception, Amateur DSR can help you push the limits of what is possible with home-built equipment. In early 2018 Paul was involved in confirming a signal reading from what is believed to be of Image, a Nasa satellite lost and presumed dead in 2005.
In this episode, Shahriar investigates the theory and experimental results of the impact of extreme low temperatures on passive and active components. Liquid Nitrogen in used in a transparent glass Dewar where different components can be fully submerged in the liquid. Various types of resistors are compared for their temperature stability. An electromagnet which uses Copper coils is used to generate a magnetic field at a constant power consumption at both extreme temperatures. The impact of liquid nitrogen on the junction voltage of an NPN device is measured as well as the frequency shift of a CMOS ring oscillator. Finally, the wavelength shift of an LED submerged in liquid nitrogen is studied. There is a puzzle at the end of this video, please share your thoughts in the comments section. The Signal Path 🤍
A cursory review of Quantum Computing instrumentation offered by BNC. Index below: 00:27 Why Quantum Computing 01:40 Superposition - The Coin Flip 02:10 Entanglement Challenges 03:01 IBM Q - A Quantum Computer Illustration 03:25 Quantum Computer Control Board and Software 03:45 Qubit Manipulation and Read-Out Instrument Rack 04:45 LO with Phase Coherency 05:22 BNC Model 855 Design Features for Coherent Signals 06:11 Phase Matched Outputs for Qubit Manipulation 06:40 Video Example - Phase Matched Outputs 08:27 Phase Coherent Switching for Qubit Manipulation 09:09 Video Example - Phase Coherent Switching 11:00 Phase Memory for Qubit Manipulation 11:41 Video Example - Phase Memory During Phase Discontinuity 13:01 Arbitrary Waveform Generators for Quantum Computing 15:35 Synchronization of Pulse Sequences to Manipulate Qubits 16:40 Waveform Editor, Hann Echo Sequence, Carr Purcell Meiboom Sequence 18:12 World's Fastest ARB with 4GSamples Memory, Uhrig Dynamic Decoupling 18:50 Quantum Sensing Applications 19:45 Trapped Ions, Nuclear Spin and other QC Elements 20:40 Remote Access and SCPI for ARB Setup and Operation (Matlab, LAN, etc) 14:04 IBM and Google launch 50 Qubit Systems 21:30 Vector Signal Generators to Stream Digital IQ Data, FCP PORT 22:32 What about the Qubit Fridge 23:33 The Qubit Fridge at 15 Milli kelvin 24:40 The Qubit Fridge Readout 25:23 Functional Block of a Qubit Readout 29:03 Why we cool down LNAs 30:05 Benefits of Measuring Noise Parameters 32:39 Obtaining Optimal Admittance 33:02 Josephson Parametric Amplifier (Minimum Noise Figure) 33:45 How to Make a Noise Parameter Measurement at Cryo Temps 36:10 Model 8060C - A Compact Impedance Generators Inside the Cryostat 36:55 Example Data from Cryo-LNA Measurements 39:09 Wrap up and Contact Info
Presenter: Dr. Slavica Jonic IMPMC-UMR 7590 CNRS, Sorbonne Université, Paris, FRANCE Single-particle cryo electron microscopy (cryo-EM) allows 3D reconstruction of multiple conformations of purified biomolecular complexes from their 2D images. The elucidation of different conformations is the key to understanding molecular mechanisms behind biological functions of the complexes and the key to novel drug discovery. The standard cryo-EM data analysis procedures involve many rounds of 2D and 3D classifications to disentangle and interpret the combined conformational, orientational, and translational heterogeneity. Gradual conformational transitions give rise to many intermediate conformational states. Continuous conformational heterogeneity in cryo-EM data (a mixture of many intermediate conformational states), due to such gradual conformational transitions, is both an obstacle for high-resolution 3D reconstruction of different states and an opportunity to obtain the information about multiple coexisting states at once. HEMNMA method [1], was specifically developed for analysing continuous conformational heterogeneity in cryo-EM data, determines the conformation, orientation, and position of the complex in each single particle image by analysing images using normal modes (motion directions simulated for a given atomic structure or EM map), which in turn allows determining the full conformational space of the complex but at the price of high computational cost. Recently, a deep learning extension of HEMNMA, referred to as DeepHEMNMA [2], was proposed, which speeds up HEMNMA by combining it with a deep learning approach. DeepHEMNMA will soon be available in ContinuousFlex, an open-source software package that my team is developing. ContinuousFlex provides a user-friendly graphical interface to several methods for analysing continuous conformational heterogeneity in vitro [1-3] and in situ [4-5]. ContinuousFlex is currently available as a plugin for Scipion [6]. In this talk, DeepHEMNMA will be presented and its performance using synthetic and experimental cryo-EM images. ContinuousFlex will also be briefly introduced. [1] 🤍 [2] 🤍 (in press) [3] 🤍 [4] 🤍 [5] 🤍 [6] 🤍 About Dr. Jonic: Slavica Jonic received the BSc and MSc degrees in electrical engineering from the University of Belgrade, Serbia, in 1996 and 1999, respectively; the PhD degree in image processing from the Swiss Federal Institute of Technology in Lausanne - EPFL, Switzerland, in 2003; and a Research Director Habilitation from the University Pierre and Marie Curie – UPMC (current Sorbonne University), France, in 2015. She held Research and Teaching Assistant positions at the University of Belgrade (1996-1999) and the EPFL (2000-2003), and a Research Scientist position at the UPMC (2004-2008). She obtained an Associate Scientist position at the French National Centre for Scientific Research (CNRS) in 2008 and a CNRS Research Director position in 2019. She is currently with the IMPMC – CNRS UMR 7590 laboratory, located at Sorbonne University, since 2004. Her background is in signal and image processing for biomedical engineering applications. She currently leads a team working in the area of methods development for the reconstruction of structure and dynamics of biological macromolecular complexes from cryo electron microscopy and cryo electron tomography data. Her particular interest is in new methods for studying continuous conformational transitions of complexes, including hybrid methods combining image analysis, molecular mechanics simulation, and deep learning. Chair: Dr. Sepideh Valimehr, CCeMMP Post Doc, Bio21
Using a hybrid approach, Lori Passmore's group aims to establish fundamental principles underlying the assembly of multi-protein complexes, define their structures, gain insight into their activities and regulation, and identify roles for proteins of unknown function. As cryo-EM is rapidly evolving, they are developing new methods to help determine protein structures. Read more about Lori's work here: 🤍 Download the lecture presentation here: 🤍 You can find more videos from the 2017 LMB Cryo-EM course here: 🤍 Other playlists you might be interested in: Electron Cryo-Microscopy Course 2014 - 🤍 Electron Cryo-Microscopy - 🤍 RELION - 🤍 Research Highlights from our Structural Studies Division - 🤍 About the MRC Laboratory of Molecular Biology (LMB): The LMB is one of the world's leading research institutes. Discoveries and inventions developed at the LMB, for example DNA sequencing and methods to determine the structure of proteins, have revolutionised all areas of biology. Its scientists work to advance understanding of biological processes at the molecular level. This information will help us to understand the workings of complex systems, such as the immune system and the brain, and solve key problems in human health. More links: Official Site: 🤍 Facebook: 🤍 Twitter: 🤍 Instagram: 🤍 LinkedIn: 🤍 Click here to subscribe to MRC Laboratory of Molecular Biology on YouTube: 🤍
IEEE CAS SCV Webinar "Designing digital modules for high-speed read-out in cryogenic TPC detectors" Aseem Gupta, SLAC, Instrument Division, Stanford University, 5/27/2021.
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